My experience with Arduino on Ubuntu was excruciatingly painful. On Windows everything seems to just work :man_shrugging: . After some digging up I tried the following and it actually helped a lot.
Hopefully one of them will work for you -

1. Turn off all powersaving like powertop and tlp.
2. Turn off bluetooth connections like speakers, headphones.
3. Double-click the reset button in quick succession.
4. sudo apt-get purge modemmanager
5. sudo chmod a+rw /dev/ttyACM0

6. sudo usermod -a -G tty <username> OR sudo usermod -a -G tty $USER
   sudo usermod -a -G dialout <username> OR sudo usermod -a -G dialout $USER
   

7. sudo chmod a+rw /dev/ttyUSB0

8. sudo chown username /dev/ttyUSB0

9. sudo chown username /dev/ttyACM0

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